ABSTRACT
Objective To observe the therapeutic effects of comprehensive rehabilitation treatment in patients with chronic renal failure (CRF). Methods Fifty patients with CRF were randomly and equally divided into a rehabilitation group and a control group. Those in the rehabilitation group were intervened with comprehensive rehabilitation protocol including regular counseling, health education and adequate aerobic exercise in addition to routine medications, while those in the control group with the routine medications only. The therapeutic effects were evaluated by means of Symptom Check List- 90(SCL- 90) and the questionnaire about quality of life (QOL) for patients with CRF, as well as such biochemical parameters as SCr, BUN, Ccr, DBP and SBP before and after treatment. Results Compared with those in the control group, the physiological capability and other relevant parameters of QOL in the rehabilitation group were significantly improved after one year of comprehensive rehabilitation, while SBP and DBP significantly decreased. There was no statistically significant changes of the concentrations of Scr, Bun, and Ccr. Conclusion Comprehensive rehabilitation intervention is superior to routine drug therapy in terms of improving the physiological capability, decreasing the BP and improving the QOL of the CRF patients.